Capabilities
The Molecular Biology Labs host a team of dedicated laboratory and data analysts who perform DNA sequencing and associated cell and ecosystem function methodologies. We conduct high-throughput DNA sequencing and computational analysis on a range of different matrices, including water, soils, animals, animal products and plants. Our laboratories are equipped for: (1) DNA extraction; (2) DNA amplification and quantification (in a dedicated clean PCR laboratory); (3) DNA sequencing; (4) Cellular analysis using flow cytometry and flow cytometric cell sorting; (5) Analysis of microbial function using extracellular enzyme assays and respirometry; and (6) Microbiology culturing in Class II laboratories. Genomic data analysis is performed on in-house bioinformatic data servers.
Lifecycle
The Molecular Biology Laboratories opened in 2010 to provide an ongoing service for UKCEH research. Equipment is maintained and replaced on a constant cycle, either at end-of-life or as newer technologies become available.
Uniqueness
The individual components of the Molecular Biology facility are not unique, and many can be found in molecular biology laboratories both nationally and worldwide. Our uniqueness lies in the technical skills and experience of our staff in knowing how to handle and analyse a wide range of environmental samples, from water, sediments, soils and other complex biological matrices such as sewage.
Partners
No external partners help to operate the UKCEH Molecular Biology Labs.
Access
The UKCEH Molecular Labs may be available to other research organisations, usually in collaboration with UKCEH: initial enquiries via Daniel Read dasr@ceh.ac.uk
Location
The Molecular Biology Labs are based at UKCEH Wallingford.
Funding sources
UKRI-NERC National Capability (LTSS): UK-SCaPE programme. Research project grants including UKRI-NERC Discovery Science Grants. UK Water Industry Research (UKWIR) and other industry users.
Users
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The Molecular Biology Labs provide analysis, advice, training and support to: UKCEH staff and PhD students; researchers from UK universities and research institutes; and the private sector.
Last updated
11 November 2022 16:18
